Կենսաբանության ֆակուլտետ
Faculty of Biology
Faculty of Biology of Yerevan State University has been established in 1933. :
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Nikolay V. Avtandilyan

Assistant | Chair of Biochemistry, Microbiology and Biotechnology
Education
2004 - 2008: Yerevan State University, Faculty of Biology, Department of Biochemistry, BSc.
2008 - 2010: YSU, Department of Biochemistry, MSc.
2010 - 2013: PhD at the Department of Biochemistry, YSU, Yerevan, Armenia

Scientific degree
PhD in Biological Science, “The role of ureotelic and nonureotelic arginases in polyamine biosynthesis”, YSU, Faculty of Biology, Yerevan Armenia

Work experience
2013 - 2014: Senior laboratory assistant at the Department of Biochemistry of Yerevan State University, Yerevan, Armenia.
2015 - 2016: Head of Educational Laboratory, Department of Biochemistry, YSU.
2014 - till now: Junior researcher at the Department of Biochemistry of Yerevan State University, Yerevan, Armenia.

Scientific interests
Biochemistry, enzymology, biomedicine, Cancer biochemistry

Participation in grant projects (present and past)
2012: Travel grant, FEBS Sofia “School of Protein Science: Structure and Dynamics of Biological Macromolecules”, September, Bulgaria.
2016 - 2018: Grant from Ministry of Education and Science of Armenia, State committee of science, the research project № 16YR-1F023 “Arginase and nitric oxide synthase: old enzymes with new perspectives in breast anticancer therapy”. Head of Scientific Group.

Professional Membership
Member of Council of “Young Biologists Association” NGO.
Member of Armenian Association of Biochemists (Federation of European Biochemical Societies) NGO.

Languages
Armenian (native), Russian (Advanced), English (Upper intermediate)

nv.avtandilyan@ysu.am

Latest Publications (19)
A. Mamikonyan, H. Javrushyan, N. Avtandilyan , Р. Арутюнян , A. Trchounian
Suppression of tumor progression by arginaseand NO-synthase combined inhibition in7,12- dimethylbenz(a)anthracene-inducedbreast cance r in rats
2021 | Thesis
FEBS Open Bio, 45th FEBS Congress, Molecules of Life: Toward New Horizons, 03-08.07.2021, p. 413, Slovenia
N. Avtandilyan , A. Mamikonyan, H. Javrushyan, A. Trchounian
Suppression of tumor progression by arginaseand NO-synthase combined inhibition in7,12- dimethylbenz(a)anthracene-inducedbreast cance r in rats
2021 | Thesis
FEBS Open Bio, 45th FEBS Congress, Molecules of Life: Toward New Horizons, 03-08.07.2021, p. 413, Slovenia
N. Avtandilyan , H. Javrushyan, M. Ginovyan, A. Trchounian
New Therapeutic Approaches In Breast Anticancer Treatment Using Armenian Herbal Extracts
2021 | Article
Biological Journal of Armenia, 2021, N 1 (73), p. 32-38
N. Avtandilyan , H. Javrushyan, A. Trchounian
The effects of NO on the urea cycle pathway in short-term intermittent hypobaric hypoxia in rats
2021 | Article
Respiratory Physiology & Neurobiology, 2021, 285, 103598
Oxidative stress in the 7,12-dimethylbenz[a] anthracene rat model of breast cancer: suppression by a NO-synthase inhibitor NG- nitro-L-arginine methyl ester
2019 | Thesis
The 44th FEBS Congress “From molecules to living systems”. 2019, pp. 341-341
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Inhibition of Tumor Progression by NG-Nitro-L-arginine Methyl Ester in 7,12- dimethylbenz(a)anthracene Induced Breast Cancer: Nitric Oxide Synthase Inhibition as an Antitumor Prevention
2019 | Article
Journal of mammary gland biology and neoplasia. 2019, Volume 24, Issue 2, pp. 1-11
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Mamikonyan A., Avtandilyan N. , Javrushyan H., Trchounian A.
Inhibition of nos activity as an effective anticancer therapy against 7,12-DMBA rat model of breast cancer
2018 | Thesis
International conference „Smart Bio“. 2018, p. 114
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G. Petrosyan, N. Avtandilyan , H. Javrushyan, A. Trchounian
Arginase is an enzyme with real tricks in antitumor treatment of 7,12-dimethylbenz(a) anthracene induced breast cancer in rats
2018 | Article
The 43rd FEBS Congress "Biochemistry Forever". 2018, 385-386 pp.
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The potential therapeutic effect of nor-NOHA and L-NAME in breast cancer treatment
2018 | Thesis
FEBS workshop on Emerging issues of breast cancer research: tumour heterogeneity, immunotherapy, and cellular metabolism. 2018, էջ ID 28993
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Nikolay Avtandilyan , Hayarpi Javrushyan, Gayane Petrosyan, Armen Trchounian
The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer
2018 | Article
BioMed Research International. 2018, Volume 2018, 8696923, 9 p.
H. Javrushyan, N. Avtandilyan , A. Mamikonyan, A. Trchounian
The change of polyamines and nitric oxide quantities in human blood serum of prostate and bladder cancer
2017 | Article
Biological Journal of Armenia. 2017, 69, 1, 125-132 pp.
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Mariam Sargsyan, Hermine Gevorgyan, Hermine Gevorgyan , Susanna Karapetyan
Changes of arginase activity and arginase isoenzyme spectrum in human serum during different stages of breast cancer before surgery and after chemotherapy
2017 | Article
ԵՊՀ ՈՒԳԸ գիտական հոդվածների ժողովածու: 2017, 1.5 (22), էջ 176-183
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Sargsyan M. S., Avtandilyan N. V. , Karapetyan S. A.
The change of arginase activity in the serum of patients diagnosed with breast cancer
2016 | Thesis
The 20th international pushchino school conference of young scientists “BIOLOGY – THE SCIENCE OF THE XXI CENTURY”. 2016, p. 167
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Геворгян Э. Р., Автандилян Н. В. , Карапетян С. А.
Изменение аргиназной активности и количества полиаминов в сыворотке крови при злокачестенных опухолях предстательной железы
2016 | Thesis
20-я Международная Пущинская школа-конференция молодых ученых «БИОЛОГИЯ - НАУКА XXI ВЕКА». 2016, стр. 174
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Avtandilyan N. V. , Karapetyan S. A., Alexanyan K. A.
The change of arginase activity in blood serum during breast and prostate cancers
2016 | Article
Electronic journal of natural sciences, 2016, 1 (26), 12-14 pp.
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Avtandilyan N. V. , Karapetyan S. A., Aleksanyan K. A.
The relationship between arginase activity and change of polyamines quantity in human blood serum during breast cancer
2016 | Article
Biological Journal of Armenia, 2016, 2 (68), 92-99 pp.
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Պոլիամինների քանակության փոփոխության ուսումնասիրումը լյարդի արգինազի իզոֆերմենտների արգելակման ժամանակ
2015 | Article
ԵՊՀ ՈՒԳԸ գիտական հոդվածների ժողովածու, 2015, 1.1 (4), բնական գիտություններ, էջ 75-81
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Relationship between liver polyamines quantity and arginase isoenzymes activity after arginase inhibition by NG-hydroxy-L-arginine
2015 | Article
National Academy of Sciences of RA, Electronic Journal of Natural Sciences, 1 (24), 2015, pp. 3-6
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Avtandilyan N. V. , Karapetyan S. A., Aleksanyan K. A.
The relationship of blood serum arginase activity and polyamines quantity during human breast cancer
2015 | Article
The New Armenian Medical journal. 2015, Vol.9, N, 10 - 10 pp.
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