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Susanna G. Tiratsuyan
Assistant | Faculty of Biology Education
1970-1975 Yerevan State University, Biological Faculty, Department of Biophysics, Diploma of Honor, Yerevan 1976-1980 PhD student of Yerevan State University, Biological Faculty, Department of Biophysics. Academic degree Candidate of Biological sciences, PhD theme: “Effect of gibberellin and other biological active substances on a chromatin and activity of some germinating wheat germs enzymes” 4th of July, 1984, YSU council Professional experience 1975 - present Scientific researcher in group of “Molecular Biophysics Laboratory” in Yerevan State University, Biological Faculty, Department of Biophysics. 1975 - 1977 - Charencavan institute of amino acid March – April, 1980 - academic mission in Molecular oncology institute of Vien University, Austria 2007 - present – assistant, Yerevan State University, Biological Faculty, Department of Biophysics. 2008 – present - associate professor Russian-Armenian University, Medical-biology faculty Academic courses Modern research methods Cell Engineering Biophysics’ actual problems Scale of professional interests Investigation of molecular-cell mechanisms of action of selected herbal extracts and particular biological active components that collectively provoke a variety of physiological responses, have a wide range of medicinal applications, including cancerogenesis, atherogenesis, inflammations, neurodegeneration, autoimmune pathologies, viral/retro and bacterial diseases, progeria, skin wounds, eczema, burns, psychological disorders etc. Investigation of several classes of compounds common to most plants, including polyphenolics, flavonoids (quercetin, rutin), etc, as well as two very active classes of unique constituents – the phloroglucinols (hyperforin, adhyperforin) and the naphthodianthrones (hypericin, pseudohypericin). Hence, therapy using free-radical scavenging antioxidants has potential to prevent, delay or ameliorate many of disorders. Determination of the natural antioxidant compounds of plant extracts will help to develop new drug candidates for antioxidant therapy. Models – chemical system (DPPH stable radical) and biological – red blood cells, hemoglobin, hemolysis, plant cell and tissue cultures, microorganisms, rats. The aim of current work was to elucidate in vitro and in vivo different biological activities of various extracts, e.g. cytotoxic, photodynamic and free radical scavenging activities, determine the relationship of flavonoids composition, antiradical, antimicrobial and antihemolytic activities in chemical and biological systems; to examine the influence of HY on structure and function of Hb; evaluation of red blood cells as model system for screening of hypericin efficacy as a photodynamic agent. Participation in grant projects (present and past) • 1993 - One-off Soros grant • 2003 - Involved in Armenian National Science and Educational Fundation (ANSEF) Grant Programme (NS-82) , Supervisor Dr., Prof. H. Vardapet¬yan, Yerevan, Armenia Languages Armenian, Native English, Good Russian, Fluent French – with dictionary (+374 10) 24-16-06 |