Ֆիզիկայի ֆակուլտետ
Faculty of Physics
The process of training specialists in the field of physics and mathematics began in 1922 in YSU.:
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Evgeny Sh. Mamasakhlinov

Associate Professor | Chair of Molecular Physics
Education
1986: Graduated from Faculty of Physics, Yerevan State University

Academic degree
Dr.Sci. (03.00.02-Biophysics). Thesis: “Spatial and temporal scales in conformational transitions in biopolymers”, 2011, Yerevan State University, Yerevan, Armenia
Candidate of phys.-math. sci. (03.00.02-Biophysics). Thesis: “The helix - coil transition in polypeptides. Microscopic approach”, 1989, Institute of Physics of Georgian Academy of Science, Tbilisi

Professional experience
2006 - present: Prof. of Department of Molecular Physics, Faculty of Physics, YSU.
2006 - 2007: Head of Dept. of Grants, YSU.
1996 - 2006: Associate Prof. of Department of Molecular Physics, Faculty of Physics, YSU.
1992 - 1996: Scientific Researcher of Laboratory of the Physics of Macromolecules Department of Molecular Physics, YSU

Academic courses
"Physics of the Condensed State of Macromolecules" for 4-th year bachelor students, YSU
"Introduction to Non-Equilibrium Thermodynamics" for 1-st year magister students, YSU
"Physics of Biological and Synthetic Polymers" for 2-nd year master students, YSU

Scale of professional interests
RNA and protein folding. Conformational transitions in DNA and DNA condensation. Statistical physics of macromolecules. Non-equilibrium thermodynamics.

Participation in grant projects
1994: RYX000 from International Science Foundation
2002 - 2007: ISTC # A 301.2
2005: 05-ns-molbio-815-503 from ANSEF
2011: PS condmatth 2567 from ANSEF
2012 - 2014: Project ”Equilibrium and non–equilibrium behavior of single– and double–stranded biological molecules” from Volkswagenstiftung
2013: Project ”Dynamics of the self-assembly of DNA-coated carbon nanotubes in polymer matrix” from German Federal Ministry of Education and Research and Ministry of Education and Science RA
2013 - 2015: Kinetics and thermodynamics of translocation of nucleic acids during the sequencing in protein nano – channel

Awards received
President Prize in Natural Sciences for 2013 (26.05.2014)

Languages
Armenian, Russian, English

y.mamasakhlisov@ysu.am

Effect of ligands binding on the isotherm of hybridization of the DNA-chip
2017 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2017, 52,2, pp. 180-188
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Fluctuations in order–disorder transitions in the DNA–ligand complexes with various binding mechanisms
2017 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2017, 52, 2, pp. 173-179
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Effect of ligand binding on functionality of DNA field-effect transistor (Լիգանդի կապման ազդեցությունը ԴՆԹ-ի դաշտ-էֆեկտ փոխանցիչի գործառնության վրա)
2017 | Article
ԵՊՀ գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2017, հ. 51, #1, էջ 66–70
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Sh. A. Tonoyan , A. V. Asatryan, D. L. Hayrapetyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Possible mechanism of non-monotone behavior of helix-coil transition temperature in two-component solvent
2016 | Article
Journal of Contemporary Physics (Armenian Academy of Sciences). 2016, 51, 1, 93-98 pp.
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Armen T. Karapetian, Zareh A. Grigoryan, Yevgeni Sh. Mamasakhlisov , Mikael V. Minasyants, Poghos O. Vardevanyan
Theoretical treatment of helix-coil transition of complexes DNA with two dofferent ligands having different binding parameters
2016 | Article
Journal of biomolecular structure & dynamic. 2016, 34,1, 198-202 pp.
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A. T. Karapetian, Z. A. Grigoryan, Y. Sh. Mamasakhlisov , M. V. Minasyants, P. O. Vardevanyan
Theoretical treatment of helixcoil transition of complexes DNA with two different ligands having different binding parameters
2015 | Article
J. Biomol. Struct. Dyn., 2015, DOI: 10.1080/07391102.2015.1010584
A. Badasyan, Y. Sh. Mamasakhlisov , R. Podgornik, V. A. Parsegian
Solvent effects in the helix-coil transition model can explain the unusual biophysics of intrinsically disordered proteins
2015 | Article
J. Chem. Phys., 2015, v. 143, 014102(1-7)
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Y. Sh. Mamasakhlisov , S. Bellucci, Sh. Hayryan, H. Caturyan, Z. Grigoryan, C.-K. Hu
Collapse and hybridization of RNA: view from replica technique approach
2015 | Article
Europhys. J. E, 2015, v. 38, 100 p.(1-9)
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Generalized Model of Polypeptide Chainfor Helix-Coil Transition in Two-component Solvent
2015 | Book
J. Contemp. Phys. 50, N 4, 375 - 380 pp.(2015)
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Y. Mamasakhlisov , Sh. Hayryan, V. Morozov , C.-K. Hu
Kinetics of the long ssRNA: Steady state
2014 | Article
Europhys. Lett., 2014, v. 106, 48007(1-6)
G. N. Hayrapetyan, F. Iannelli, J. Lekscha, V. F. Morozov , R. R. Netz, Y. Sh. Mamasakhlisov
Cold melting of RNA with quenched sequence randomness
2014 | Article
Phys. Rev. Lett., 2014, v. 113, 068101(1-5)
A. V. Badasyan, Sh. A. Tonoyan , A. Giacometti, R. Podgornik, V. A. Parsegian, Y. Sh. Mamasakhlisov , V. F. Morozov
Unified description of solvent effects in the helix-coil transition
2014 | Article
Phys. Rev. E 89 022723( 2014)
Helix-coil transition in biopolymers with multicomponent heterogeneity of energy and number of conformations
2014 | Article
J. Contemp. Phys. 49, N 3, 132 (2014)
G. N. Hayrapetyan, Y. Sh. Mamasakhlisov , V. F. Morozov , V. V. Papoyan, V. B. Priezzhev
Two-dimensional random walk and critical behavior of double-strand DNA
2013 | Article
J. Phys. A: Math. Theor., 2013, v. 46, 035001(1-9)
A. Badasyan, A. Giacometti, R. Podgornik, Y. Mamasakhlisov , V. Morozov
Helix-coil transition in terms of Potts-like spins
2013 | Article
Eur. Phys. J. E, 2013, v. 36, 46, DOI 10.1140/epje/i2013-13046-7
G. N. Hayrapetyan, H. L. Tsaturyan, Sh. A. Tonoyan , Y. Sh. Mamasakhlisov
Thermodynamics of single-stranded RNA with random sequence: Constrained annealing approach
2013 | Article
J. Contemp. Phys. 48, N 2, 98 (2013)
On the theory of helix-coil transition in heterogeneous biopolymers. Constrained annealing method
2013 | Article
J. Contemp. Phys. 48, N 5, 236 (2013)
Y. Sh. Mamasakhlisov , Sh. Hayryan, C.-K. Hu
Long charged macromolecule in an entropic trap with rough surfaces
2012 | Article
Phys. Rev. E, 2012, v. 86, 051904(1-5)
A. V.Badasyan, S. A. Tonoyan , A. Giacometti, R. Podgornik, V. A. Parsegian, Y. Sh. Mamasakhlisov , V. F. Morozov
Osmotic pressure induced coupling between cooperativity and stability of a helix-coil transition
2012 | Article
Phys. Rev. Lett. 109, 068101 (2012)
A. V. Badasyan, Sh. A. Tonoyan , Y. Sh. Mamasakhlisov , A. Giacometti, A. S. Benight, V. F. Morozov
Competition for hydrogen-bond formation in the helix-coil transition and protein folding
2011 | Article
Phys. Rev. E 83 051903 (2011)
S. Bellucci, Y. Mamasakhlisov , A. Nersessian
External field influence on semiflexible macromolecules: geometric coupling
2011 | Article
Mod. Phys. Lett. B, 2011, v. 25, 1809-1819
Differential Geometry in DNA molecules
2011 | Article
Nanoscience and Nanotech. Lett., 2011, v. 3, 922-926
A. V. Badasyan, A. Giacometti, Y. Sh. Mamasakhlisov , V. F. Morozov , A. S. Benight
Microscopic formulation of the Zimm-Bragg model for the helix-coil transition
2010 | Article
Phys. Rev. E, 2010, v. 81, 021921(1-4)
Different stability of RNA secondary and tertiary structures (ՌՆԹ-ի երկրորդային և երրորդային կառուցվածքների տարբեր կայունություններ)
2009 | Article
ԵՊՀ Գիտական տեղեկագիր, Ֆիզիկա և մաթեմատիկա, 2009, #3, էջ 55–57
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A. V. Badasyan, G. N. Hayrapetyan, Sh. A.Tonoyan , Y. Sh.Mamasakhlisov , A. S. Benight, V. F. Morozov
Intersegment interactions and helix-coil transition within the Generalized Model of Polypeptide Chains (GMPC) approach
2009 | Article
J. Chem. Phys., 2009, v. 131, 115104
Y. Sh. Mamasakhlisov , B.A. Todd, A.V. Badasyan, A.V. Mkrtchyan, V.F. Morozov , V. A. Parsegian
DNA stretching and Multivalent-Cation-Induced Condensation
2009 | Article
Phys. Rev. E, 2009,v. 80, 031915(1-9)
A. V. Badasyan, Sh.A. Tonoyan , A.V. Tsarukyan, Y. Sh. Mamasakhlisov , A.S. Benight, V.F. Morozov
Two Scale Generalized Model of Polypeptide Chain
2008 | Article
J. Chem. Phys.128,195101 (2008)
Y. Sh. Mamasakhlisov , A. Naji, R. Podgornik
Partially Annealed Disorder and Collapse of Like-Charged Macroions
2008 | Article
J. Stat. Phys., 2008, v. 133, 659-681
A. V. Tsarukyan, Sh. A. Tonoyan , G. N. Hayrapetyan, I. V. Baghdyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Helix-Coil Transition in the Case of Interaction Between Two Chains
2008 | Article
J. Contemp. Phys. 43, N 5, 254 (2008)
Sh. A. Tonoyan , G. N. Hayrapetyan, A. V. Tsarukyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Generalized Model of Polypeptide Chain With Limitation on the Length of Helical Fractions
2008 | Article
J. Contemp. Phys. 43, N 4, 203 (2008)
Hybridization kinetics of DNA short fragments
2008 | Article
Electronic Journal of Natural Sciences., 2008, V. 2 (11), 3, Р. 3-6
Stochastic model of adsorption of particles on macromolecules at an arbitrary filling
2008 | Article
J. Contemp. Phys., 2008, V. 43, P.48-53
A.V. Grigoryan, E.Sh. Mamasakhlisov , T.Yu. Buryakina, A.V. Tsarukyan , A.S. Benight, V. F. Morozov
Stacking heterogeneity: A model for the sequence dependent melting cooperativity of duplex DNA
2007 | Article
J. Chem. Phys., 2007, v. 126, 165101 (1-9)
Y. Sh. Mamasakhlisov , Sh.A. Hayryan, V. F. Morozov , C.-K. Hu
RNA Folding in the Presence of Counterions
2007 | Article
Phys. Rev. E, 2007, v. 75, 061907 (1-10)
Y. Sh. Mamasakhlisov , Sh.A. Hayryan, C.K. Hu
Random Sequences with Power-law Correlations Exhibit Protein-like Behavior
2007 | Article
J. Chem. Phys., 2007, v.126, 145103 (1-10)
Complexes of bovine serum albumin with water-soluble Cu and Co containing cationic meso-tetra-(4-N-oxyethylpyridyl)-porphyrins
2007 | Article
J. Porphyrins Phthalocyanines, V 11, N 7, pp.475-480 (2007)
Sh. A. Tonoyan , T. Yu. Buryakina, A. V. Tsarukyan, Y. Sh. Mamasakhlisov , V. F. Morozov
Generalized model of polypeptide chain with two-scale interactions
2007 | Article
J.Contemp. Phys. 42, N6, 309 (2007)
A. V. Tsarukyan, Sh. A. Tonoyan , A. V. Badasyan, A. V. Grigoryan, E. Sh. Mamasakhlisov , V. F. Morozov
Order parameters of helix-coil transition in biopolymers
2006 | Article
J. Contemp.Phys., 41, N 1, 54 (2006)
Е.Ш. Мамасахлисов , А.В. Бадасян, В.Ф. Морозов , А.В. Григорян, A.В. Царукян
Влияние конкурентного и не конкурентного растворителя на переход спираль-клубок в биополимерах
2005 | Article
Известия НАН Армении, Физика, 2005, т. 40, N 2, сс. 111-115
A.V. Tsarukyan, Sh. Tonoyan, A.V. Badasyan, A.V. Grigoryan, E. Sh. Mamasakhlisov , V.F. Morozov
The helix-coil transition and definition of the order parameter in the scope of the generalized model of polypeptide chains
2005 | Article
NAS RA, Electronic Journal of Natural Sciences, 2005, v. 2, pp. 8-11
V.F. Morozov , A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasahlisov , Sh.A. Hayryan, C.-K. Hu
Helix-Coil Transition in Closed Circular DNA
2005 | Article
Physica A, 2005, v. 348C, pp. 327-338
V. F. Morozov , A. V. Badasyan, A. V. Grigoryan, M. A. Sahakyan, E. Sh. Mamasakhlisov
Stacking Decreases the Cooperativity of Melting of Homopolymeric DNA
2005 | Article
Modern Physics Letters B, v.19, 2005, pp. 79-83
A.V. Grigoryan, A.V. Badasyan, V.F. Morozov , E. Sh.Mamasakhlisov
The invariance of order parameter and temperature redefinition in helix-coil transition of circular closed DNA
2005 | Thesis
Physics of Atomic Nuclei, 2005, v.10, p. 1748
A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasakhlisov , V.F. Morozov
Order-disorder transition in one-dimensional system with disorder in composition
2005 | Article
Physics of Atomic Nuclei, 2005, v.11, p. 1984
A.V. Badasyan, A.V. Grigoryan, E.Sh. Mamasakhlisov , A.S. Benight, V.F. Morozov
The helix-coil transition in heterogeneous double stranded DNA: Microcanonical method
2005 | Article
J. Chem. Phys., 2005, 1v. 123, 194701 (1-6)
E. Sh. Mamasakhlisov , A. V. Badasyan, A. V. Tsarukyan, A. V. Grigoryan , V. F. Morozov
The generalized model of polypeptide chain describing the helix-coil transition in biopolymers
2005 | Article
Preprint of International Centre for Theoretical Physics, IC/2005/037 www.ictp.it/~pub_off
A. Tsarukyan, Sh. Tonoyan , A. Badasyan, A. Grigoryan, E. Mamasakhlisov , V. Morozov
The Helix Coil Transition and Definition of the Order Parameter in the Scope of the GMPC
2005 | Article
Electronic Journal of Natural Sciences (Biophysics) 2, 5 (2005)
А.В. Бадасян, А.В. Григорян, Е.Ш. Мамасахлисов , В.Ф. Морозов
Анализ перехода спираль-клубок в кольцевой замкнутой ДНК на основе статистической модели
2004 | Article
Известия НАН Армении, Физика, 2004, т. 39, N 4, сс. 265-270
Some dynamic properties of random heteropolymers with correlation in sequence
2001 | Article
Modern Problems of Cellular and Molecular Biophysics, Noyan Tapan, Yerevan, 2001, pp. 209-219
E.Sh. Mamasakhlisov , V.F. Morozov , Sh.A. Hayryan, C.-K. Hu
Microscopical Approach to the Helix- Coil Transition in DNA
2000 | Article
Physica A, 2000, v.281, pp. 51-59
Haroutiunian S.G. , Dalyan Y.B. , Morozov V.F. , Mamasachlissov Eu.Sh. , Shahinian M.S., Akhrem A.A., Lando D.Yu., Messori L., Orioli P.
Influence of cis- and trans-diamminedichloroplatinum(II) binding on the helix-coil transition of DNAs with different GC-content
1998 | Article
Inorganica Chimica Acta, 1998, 275-276, 510-514
The Lack of Long - Range Correlations is a Necessary Conditions of the Biologically Functional Protein
1997 | Article
J. Phys. A (Math. & Gen.) 1997, v.30, pp. 7765 – 7772
Haroutiunian S.G , Mamasakhlissov Eu.Sh. , Dalyan Y.B. , Morozov V.F. , Khachikyan R.E., Vardevanyan P.O., Karapetyan A.T, P.Oriօli, B.Bruni
The modification of the spatial structure of DNA in its complexes with cis-DDP
1997 | Article
Biophysics 1997, 42, 372-377. (in Russian)
Арутюнян С.Г., Мамасахлисов Е.Ш. , Морозов В.Ф. , Далян Е.Б. , Хачикян Р.Э., Вардеванян П.О. , Карапетян А.Т., Ориоли П., Бруни Б.
Модификация пространственной структуры ДНК в комплексе с цис-платиной
1997 | Article
Биофизика, 1997, 42(2), с.372-377
Helix-coil transition in polypeptides. A Microscopic approach II
1995 | Article
Biopolymers, 1995, v.35 N 1, pp. 75-84
Sh.A.Hairyan, N.S.Ananikyan, E.Sh.Mamasahlisov , V.F. Morozov
Helix-coil transition in polypeptides. Microscopic approach
1990 | Article
Biopolymers, 1990, v.30, NN 3/4, pp. 357-367
V. F. Morozov , Ye. Sh. Mamasakhlissov , D. M. Minasian, V. M. Aslanian
Построение статистической суммы линейной макромолекулярной системы (Գծային մակրոմոլեկուլային համակարգի ստատիստիկական գումարի կառուցումը)
1988 | Article
ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 1988, #3, էջ 162-164 (ռուսերեն)
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