Influence of nanoparticles on stability and conductivity of bilayer lipid membrane
Ministry of Education and Science of RA, State Committee of Science Contracts (thematic) funding competition in 2015, a field, Biological Sciences

Short Description

In the recent years, nanoparticles and nanomaterials have found wide application in many areas of science and practical life. They possess a number of unique properties that distinguish them greatly from the macroscopic properties of materials. It has become apparent that their application will radically change the situation in the engineering and biomedicine. Therefore, research related to the interaction of nanoparticles and nanomaterials with cells of a organism is important. These studies on one hand have to determine the degree of toxicity of nanoparticles and nanomaterials, and to reveal the possibility of their use in pharmacology and medicine, on the other. Note that for the vast majority of nanoparticles and nanomaterials mechanisms of it’s entry to the body, biocompatibility, biotransformation, translocation in tissues and organs, elimination, and, most importantly, their toxicity are not known. The interaction of nanoparticles with cell starts from cell membrane. Within this project we will study the influence of nanoparticles on the most important parameters of BLM (the model of cell membrane) - resistance, conductivity and capacitance, which in turn can help to understand mechanisms of interaction and penetration of nanoparticles into the cell through the membrane.

Project Manager
Valeri B. Araqelyan, Doctor of Phys. Math. Sciences, Professor 

Staff members

Zaven E. Navoyan, PhD,
Anahit L. Torosyan, PhD,
Karine K. Karamyan, PhD,
Hrachya A. Ishkhanyan, student

Tel.: (+374 60) 710930
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