Nelli H. Karapetyan
Biography
Education
1981: Graduated from Biophysics Department, of Biological Faculty, Yerevan State University

Academic degree
Candidate of Biological sci. (03.00.04-Biochemistry): “Physico-chemical, catalytic and immunological properties of the brain enolase isoenzymes.”, 1989, Yerevan State University

Professional experience
1997: Docent of Molecular Physics Department, Faculty of Physics, YSU
1993: Senior Scientific Researcher of Department of Molecular Physics, Faculty of Physics, YSU
1991 - 1993: Scientific Researcher ,YSU
1990 - 1991: Scientific Researcher, Institute of Molecular Biology
1987 - 1988: Invited Investigator in Budapest Institute of Enzymology, Hungary
1984 - 1990: Junior Scientific Researcher , Institute of Molecular Biology
1981 - 1984: Senior Laborant, Institute of Molecular Biology

Academic courses
"Methods of the Biopolymers Investigations" for 1-st year master students, YSU.

Scale of professional interests
Isolation of DNA and proteins. Investigation of complexes formation between some potential drugs (Pt-compounds, porphyrins, etc.) with DNA and proteins.
Investigation of the antitumor and radioprotective properties of the new synthesized compounds in vitro and in vivo experimental conditions.

Participation in grant projects
2002 - 2006: ISTC A-773
2002 - 2007: ISTC #A-301.2
2007 - 2009: ISTC A-1321
2010 - 2012: ISTC A-1764

Languages
Armenian, Russian, English

Professional membership
Armenian Biophysicists Association

nelkh@ysu.am

Nelli H. Karapetyan

Associate Professor | Faculty of Physics - Chair of Molecular Physics
 
 

Book

N. H. Karapetyan, G. V. Ananyan

«Կենսապոլիմերների ուսումնասիրման մեթոդներ» | Ուսումնամեթոդական ձեռնարկ: Երևան, 2008, 85 էջ
 

Article

N. H. Karapetyan

DNA protection from radiation damage (ԴՆԹ-ի պաշտպանությունը ճառագայթահարման վնասվածքներից ) | ԵՊՀ Գիտական տեղեկագիր: Քիմիա և կենսաբանություն, 2019, հ. 53, #2, էջ 86-90 |

Н. Г. Каpапетян, Г. В. Ананян, Е. Б. Далян, C. Г. Аpутюнян

Плавление ДНК опуxоленоcящиx кpыc, леченыx мезо-тетpа(4-n-гидpокcиэтилпиpидил)поpфиpином и его AG-, ZN-, CO-пpоизводными | Биофизика. 2017, 62, 3, стр. 458–463

N. H. Karapetyan, A. L. Torosyan, M. Malakyan, S. A. Bajinyan, S. G. Haroutiunian

Investigation of irradiated rats DNA in the presence of Cu(II) chelates of amino acids Schiff bases | Journal of biomolecular structure & dynamics. 2016, 34(1), 177-183 pp. |

N. H. Karapetyan , A. L. Torosyan, M. Malakyan , S. A. Bajinyan

Investigation of irradiated rats DNA in the presence of Cu(II) chelates of amino acids Schiff bases | Journal of Biomolecular Structure and Dynamics, 2015 p. 1-8

Karapetyan N. H., Malakyan M. H., Bajinyan S. A., Torosyan A. L., Grigoryan I. E., Haroutiunian S. G.

Influence of Amino Acids Shiff Bases on Irradiated DNA Stability In Vivo | Cell biochemistry and biophysics. 2013, 67,1137-1145 pp.

N. H. Karapetyan, L. V. Torosyan, G. V. Ananyan, R. E. Muradyan

DNA damage and anti-tumor activity induced by Zn, Ag and Co containing meso-tetra(4-N-oxyethylpyridyl)porphyrins in vivo | J. Porphyrins Phthalocyanines, 2010, v. 14, p. 349–353

S.A.Bajinyan, M.H Malakyan, V.H Matosyan, K.N Babayan, D.E.Yeghiazaryan, L.A.Vardevanyan , N.H. Karapetyan

Preventive-treatment of radiation injuries with Cu(II) chelates of amino acid Schiff bases | Biotechnology and health -2 & DAAD Alumni seminar. Int. Conf. Yerevan. April 21-25, 2008, p.25-29

Nelli H. Karapetyan, Lusine R. Aloyan, Robert K. Ghazaryan , Yevgeni Mamasakhlisov

Complexes of bovine serum albumin with water-soluble Cu and Co containing cationic meso-tetra-(4-N-oxyethylpyridyl)-porphyrins | J. Porphyrins Phthalocyanines, V 11, N 7, pp.475-480 (2007)

N.H. Karapetyan, L.V. Torosyan, M.H.Malakyan, S.A.Bajinyan

Effects of Nicotinyl-L-Tyrosinate and Nicotinyl-L-Tryptophanate on Irradiated DNA Stability in vivo | New Polymers and Radioprotectors for Biology and Medicine. Int. Conf. Yerevan. 2007, 90-91

N.H.Karapetyan, G.V.Ananyan, L.V.Torosyan, Y.B.Dalyan

Structural features of the Tumor’s DNA on the presence of AgT4OEPyP | Vestnik SPbSU.Ser.4 Physics, Chemistry, 2007, #2, 53-57 (in Russian)

N.H.Karapetyan, L.R. Aloyan, R.K.Ghazaryan, Y.Mamasakhlisov

Complexes of Bovine Serum Albumin with Cu and Co containing Cationic Meso-tetra-(4-N-oxyethylpyridyl)Porphyrins | J. Porphyrins and Phthalocyanines, 2007, 11, 475-480

N. H. Karapetyan, K. K. Karamyan, Ye. B. Dalyan

Зависимость термодинамических параметров ДНК фасоли от содержания 137Cs и 40K (Լոբու ԴՆԹ-ի ջերմադինամիկ պարամետրերի կախվածությունը 137Cs-ի և 40K-ի պարունակությունից) | ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 2006, #2, էջ 97-104 (ռուսերեն) |

N.H. Karapetyan, V.N. Madakyan

Interaction of new porphyrins with bovine serum albumin | Bioorganic chemistry. 2004, v.30, #2, p.1-6. (in Russian)

Tikunov B. , Vardevanyan P.O., Gevorgyan E.S., Dalyan E.B, Karamyan K.K., , Karapetyan N.H

Stability of the DNA and grow parameters of wheat seeds of Armenian NPP location regions | Proceedings of the International Conference URM 2004, Yerevan, 2004, p.64-70

J.Batke, K.B. Nazarian, N.H.Karapetian

Complex of Brain D-Phosphoglycerate Mutase and (y)-Enolase and its Reactivation by D-Glycerate2,3 | Biphosphate.-Archives of Biochemistry and Biophysics (1988), v.264, No 2, 510-518

S.G. Haroutiunian , E.B. Dalian, N.H.Karapetian

The Specific Influence of External Medium on Order-Desorder Transition of DNA | Int. Symp.Yerevan, 1998

S.G. Haroutiunian , P.O. Vardevanian , E.B. Dalian , A.T. Karapetian , G.A. Terzikian , N.H.Karapetian

The possible Structure DNA modifications in the presense of cisplatinum | Int. Conf. on Molecular Structural Boilogy, Viena, 1995

N.H.Karapetian

Interaction of Phosphoglyceratemutase with Enolase Isoenzymes | Neurochemistry- (1992), v.11, No3, 108-113(in Russian)

K.B. Nazarian, N.H.Karapetian, B.A.Kazarian

Differences in Stability of (αα)- and (γγ)-Enolase Isoenzymes of the Brain During Incubation with Neutral Salts | Neurochemistry- (1990), v.9, No2, 217-224 (in Russian)

J. Batke, K. B. Nazarian, N. H. Karapetian

Complex of Brain D-Phosphoglycerate Mutase and γ-Enolase and its Reactivation by D-Glycerate2,3-Biphosphate | Archives of Biochemistry and Biophysics (1988), v.264, No 2, 510-518

K.B. Nazarian, B.A.Kazarian, N.H.Karapetian

Some Function of Characteristics of Mammalian Enolase Isoenzymes | Biochemistry J.of Ukraine (1986) v.58, No.4, 72-76 (in Russian)

K.B. Nazarian, B.A.Kazarian, N.H.Karapetian

Purification and Some Physico-Chemical Properties of Bovine Brain Enolase Isoenzymes | Neurochemistry- (1985) v.4, No.4, 410-414 (in Russian)

L. G. Muradian, N. A. Karapetian

Карпо-анатомическая характеристика некоторых представителей семейства ворсянковых (Dispsacaceae) (Dispsacaceae ընտանիքի որոշ կովկասյան ներկայացուցիչների կաչպո-անատոմիական բնութագիրը) | ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 1981, #2, էջ 95-104 (ռուսերեն) |
 

Thesis

Gayane V. Ananyan, Nelli H. Karapetyan, Vigen G. Barkhudaryan

Molecular alterations in DNA under UV-irradiation | Albany 2019: The 20th Conversation. 2019, p. 86

N. Karapetyan, H. Toneyan, A. Kutuzyan, L. Mouradian

Spectron’s phase peculiarities: numerical study | 4th International Simp. Optics & its applications. 2016, p. 40

G. V. Ananyan, N. H. Karapetyan, S. G. Haroutiunian, Y. B. Dalyan

The features of complex formation of poly(dI-dC)2with porphyrins | Albany 2015:19th Conversation Journal of Biomolecular Structure and Dynamics, V.33, S.1., 2015, p. 85. DOI:10.1080/07391102.2015.1032765

G. V. Ananyan, N. H. Karapetyan, S. G. Haroutiunian, Y. B. Dalyan

The features of complex formation of poly(dI-dC)2 with porphyrins | J. Biomolecular Structure and Dynamics, Vol. 33, S1, No.132, p.85, (2015)

N. H. Karapetyan

The features of complex formation of tumor DNA with Zn-porphyrin | International Conference. Physical Concepts of Nucleic-Acid Structure and Behavior Funded by VolkswagenStiftung, the state Committee of Science (Armenia) and ICTP network NET6827-29 May, 2013, Yerevan, Armenia. p. 40-41

N.H. Karapetyan, A.L. Torosyan, I.E. Grigoryan, A.A. Gazaryan, M. Malakyan, S.A. Bajinyan

Microcalorimetric and Electrophoretic Investigations of Irradiated Rats DNA in the Presence of Mn(II) Chelates of Aminoacids Shiff Bases | An International Symposium on Solvation and Ionic Effects in Biomolecules: Theory to Experiment, May 17-21, 2010, Tsakhkadzor, Armenia, Abstract Book, p. 38

N.H. Karapetyan, A.L. Torosyan, M. Malakyan, S.A. Bajinyan

Radioprotective effects of Mn(II)(Nicotinil-L-Tyrosinate)2 and Mn(II)(Nicotinil-L-Tryptophanate)2.Improved melting characteristics of irradiated rats liver DNA | 37th Annual Meeting of the European Radiation Research Society, 26th-29th August 2009, Prague, Czech Republic, Abstract Book, p. 69

A.L. Torosyan, A.L. Arevshatyan, N.H. Karapetyan

Study of irradiated DNA melting parameters in the presence of Cu(II)(Nicotinil-L-Tyrosinate)2 and Cu(II)(Nicotinil-L-Tryptophanate)(2) | The Young Scientists Conference ”Perspective for development of molecular and cellular biology”, May 5-6, 2008, Yerevan, Armenia, Abstract Book, p.15

Ananyan G. V, Aloyan L.R, Karapetyan N.H, Dalyan Y. B

Interaction of Mn(III)-containing porphyrins with DNA | Int.Conf. “New Polymers and Radioprotectors for Biology and Medicine”. Yerevan, Armenia, 8-10 October, p.11-12, 2007

Karapetyan N.H, Torosyan L.V., Ananyan G. V., Dalyan Y. B

B Сравнительное исследование параметров плавления ДНК в тканях здоровой, опухоленосящей и леченной порфирином мыши, в присутствии Mn2+ | Int.Symposium under the auspieces of UNESCO dedicated to the centenary of Academician N.M.Sissakian’s birth. "Problems of biochemistry, molecular, radiation biology and genetics". Yerevan-Ashtarak, 2007, p.55,

Карапетян Н.Г, Ананян Г.В., Далян Е.Б

Влияние AgT4OEPyP на термодинамические особенности опухолевой ДНК | Конф. “Современные проблемы молекулярной биофизики”, Санкт-Петербург 15-16 июня, 2006. с.37

N. H. Karapetyan, M. K. Poghosyan, R. K. Ghazaryan

Spectral Study of New Pyridyl Porphyrins with Bovin Serum Albumin | International Symposium on Hydration and Termodynamics of Molecular Recognition. March 1-5, 2005, P. 53. Tsakhkadzor, Armenia

N.H.Karapetyan, Y.B.Dalyan, K.K.Karamyan, P.O.Vardevanyan, E.Gevorgyan

Evaluation of the DNA stability and grow parameters of bean seeds of Armenian NPP location regions | International Conference dedicated to N.W.Timofeeff-Ressovsky ,,Modern Problems of Genetics, Radiobiology, Radioecology and Evolution,, Yerevan, September 8-11, 2005, P.119

Y. Dalyan, N. Karapetyan, S. Haroutiunian, G. Ananyan, L. Aloyan, V. Vardanyan, T. Chalikian

Binding of New Meso-Tetra-(3N-Pyridil) Porphyrins to DNA | HUPO 2nd Annual and IUBMB XIX World Congress, October 8-11, Monreal.Molecular and Cellular Proteomics, 2003. v.2, # 9, p.972