Susanna G. Tiratsuyan
Biography
Education
1970-1975 Yerevan State University, Biological Faculty, Department of Biophysics, Diploma of Honor, Yerevan
1976-1980 PhD student of Yerevan State University, Biological Faculty, Department of Biophysics.

Academic degree
Candidate of Biological sciences, PhD theme: “Effect of gibberellin and other biological active substances on a chromatin and activity of some germinating wheat germs enzymes” 4th of July, 1984, YSU council

Professional experience
1975 - present Scientific researcher in group of “Molecular Biophysics Laboratory” in Yerevan State University, Biological Faculty, Department of Biophysics.
1975 - 1977 - Charencavan institute of amino acid
March – April, 1980 - academic mission in Molecular oncology institute of Vien University, Austria
2007 - present – assistant, Yerevan State University, Biological Faculty, Department of Biophysics.
2008 – present - associate professor Russian-Armenian University, Medical-biology faculty

Academic courses
Modern research methods
Cell Engineering
Biophysics’ actual problems

Scale of professional interests
Investigation of molecular-cell mechanisms of action of selected herbal extracts and particular biological active components that collectively provoke a variety of physiological responses, have a wide range of medicinal applications, including cancerogenesis, atherogenesis, inflammations, neurodegeneration, autoimmune pathologies, viral/retro and bacterial diseases, progeria, skin wounds, eczema, burns, psychological disorders etc. Investigation of several classes of compounds common to most plants, including polyphenolics, flavonoids (quercetin, rutin), etc, as well as two very active classes of unique constituents – the phloroglucinols (hyperforin, adhyperforin) and the naphthodianthrones (hypericin, pseudohypericin). Hence, therapy using free-radical scavenging antioxidants has potential to prevent, delay or ameliorate many of disorders. Determination of the natural antioxidant compounds of plant extracts will help to develop new drug candidates for antioxidant therapy.
Models – chemical system (DPPH stable radical) and biological – red blood cells, hemoglobin, hemolysis, plant cell and tissue cultures, microorganisms, rats.
The aim of current work was to elucidate in vitro and in vivo different biological activities of various extracts, e.g. cytotoxic, photodynamic and free radical scavenging activities, determine the relationship of flavonoids composition, antiradical, antimicrobial and antihemolytic activities in chemical and biological systems; to examine the influence of HY on structure and function of Hb; evaluation of red blood cells as model system for screening of hypericin efficacy as a photodynamic agent.

Participation in grant projects (present and past)
• 1993 - One-off Soros grant
• 2003 - Involved in Armenian National Science and Educational Fundation (ANSEF) Grant Programme (NS-82) , Supervisor Dr., Prof. H. Vardapet¬yan, Yerevan, Armenia

Languages
Armenian, Native
English, Good
Russian, Fluent
French – with dictionary

(+374 10) 24-16-06

Susanna G. Tiratsuyan

Assistant | Faculty of Biology
 
 

Book

Vardevanyan P.O., Panosyan G., Vardapetyan H., Tiratsuyan S.G., Babayan Yu.

Structural changes in wheat DNA during germination | Studia biophysica 1983, 97, N3, s. 209-212
 

Article

Vardapetyan H.R., Tiratsuyan S.G., Gonyan S.A.

Electrokinetic properties of isolated liver hepatocites during their activity changes | Plant Physiology, 1996, v. 4, N4, p. 616-619

Vardapetyan H.R., Tiratsuyan S.G., Vardevanyan P.O., Bojagyan B.G., Panosyan G.A.

Study of grow wheat embryo oligonucleosomes fortified with transcriptionally active genes | Plant Physiology, 1995, v. 42, N 2, p. 290-294

H. R. Vardapetian, A. B. Kirakossian, S. G. Tiratsuyan, G. H. Panossian

Параметры роста клеточных культур некоторых сортов пшеницы (Ցորենի որոշ սորտերի բջջային կուլտուրաների աճի պայմանները) | ԵՊՀ Գիտական տեղեկագիր, Բնական գիտություններ, 1994, #1, էջ 80-87 (ռուսերեն) |

Гонян С.А., Тирацуян С.Г., Вардеванян П.О.

Поверхностный заряд изолированных ядер гепатоцитов при измерении их функциональной активности | Биофизика, т.58, 1993, N5, с. 887-888

Vardapetyan H.R., Gonyan S.A., Tiratsuyan S.G.

Surface charge of isolated hepatocites nuclei during their activation measurements | Biophysics, 1993, v. 38, N 5, p. 887, (IF 1.857)
1   2   3   4   5  |  See all