Tatevik H. Sargsyan
Biography
Education
Yerevan State University, Faculty of Chemistry, Pharmaceutical Chemistry Specialization: pharmacist-chemist, pharmaceutist

Academic degree, rank
PhD in chemistry

Dissertation/thesis topic
“Synthesis of di- and tripeptides containing functionally-substitute nonproteinogenic α-amino acids and their effect on activity of serine proteases”, 2012, Scientific and Production Center “Armbiotechnology” NAS RA

Scope of scientific interests
Synthesis of short peptides containing potentially biologically
active non-protein amino acids

Lectures delivered
General hygiene

Professional activities
2015 up to present: Asistant at YSU Institute of Pharmacy
2011: researcher at the Laboratory of the Synthesis of Peptides and 2016 up to present researcher at the Laboratory of the Synthesis of Non-Protein Amino Acids and Peptides of the Scientific and Production Center “Armbiotechnology” NAS RA
2012 - 2015: Laboratory Assistant at the Faculty of Chemistry of the Department of Pharmaceutical Chemistry
2008 - 2010: Junior Researcher at the Laboratory of Asymmetric Synthesis of the Research Institute of Biotechnology

Membership
“Armenian Biotechnological Association” (NGO)

Grants
ISTC/#A-1677 “The synthesis of potential biologically active heterocycle substituted a-amino acids and peptides. Investigation of their antibacterial, antiviral and antitumor properties” 2009 - 2012 (36 months)
Ministry of Education and Science of Armenia, State Committee of Science 13-2I117: “The screening of biologically active short peptides containing non-protein amino acids via “Pass-online” software and their target synthesis” 2013 - 2015 (24 months)
Ministry of Education and Science of Armenia, State Committee of Science 15T-2I215: “Modeling and targeted synthesis of short peptides as potential inhibitors of serine proteases and their effect on the activity of enzymes” 2015 - 2017 (24 months)
STC/#A-2289 2017 - 2020 (36 months)

Qualification courses
2016 - 2021: YSU lecturers' qualification improvement courses

Languages
Armenian, Russian, English

Tatevik H. Sargsyan

Candidate of Chemistry, Assistant | Institute of Pharmacy - The Chair of Biomedicine
 
 

Article

Tatevik Hovhannes Sargsyan, Ani Slavik Dadayan, Lala Ashot Stepanyan, Anahit Mkhitar Hovhannisyan, Slavik Arshak Dadayan

Quantitative analysis of biologically active substances and the investigation of antioxidant and antimicrobial activities of some extracts of Osage orange fruits | Pharmacia 2021, 68 (4)l p. 731-739, doi: 10.3897/pharmacia.68.e70180

T.H. Sargsyan, A.M. Hovhannisyan, A.S. Sargsyan, G.F. Mkrtchyan

Study of peptides bioactivity synthesized on the basis of (S)-a-allylglycine non-protein amino acid | Chemical journal of Armenia 2021, № 74, p. 48-58

Sargsyan, T. H., Jamgaryan, S. M., Gyulumyan, E. A., Sargsyan A. S., Hakobyan, H. I., Mardiyan, Z. Z., Saghyan, A. S.

Targeted synthesis of N-tertbutoxycarbonylglycyl-(S)-α-allylglycyl-(S)-alanine tripeptide and study of its effect on collagenase activity | Chemical journal of Armenia 2021, № 74, p. 58-65

T. H. Sargsyan, Yu. M. Danghyan, S. M. Jamgaryan, E. A. Gyulumyan, N. S. Khachaturyan, S. A. Gevorgyan, H.I. Hakobyan, Z. Z. Mardiyan, A. S. Saghyan

synthesis of N-tert-butyloxycarbonylglycyl-(S)--[4-allyl-3-propyl-5-thioxo-1,2,4-triazol-1-yl]--alanine dipeptide and study of its antifungal effect | Chemical journal of Armenia 2019, № 72, p. 495-501

T. H. Sargsyan, YU. M. Danghyan, S. M. Jamgaryan, A. S. Sargsyan, E. A. Gyulumyan, N. A. Hovhannisyan, A. M. Hovhannisyan, A. H. Tsaturyan, H. A. Panosyan, A. S. Saghyan

Targeted synthesis of 9-fluorenylmethyloxycarbonylglycyl-(S)-β-[4-allyl-3-propyl-5-thioxo-1,2,4-triazol-1-yl]-α-alanine and study of its effect on collagenase activity | Chemical journal of Armenia 2018, № 71, p. 571-578
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Thesis

T.H. Sargsyan, A.M. Hovhannisyan, G.F. Mkrtchyan, N.A. Hovhannisyan, M.S. Ghazaryan, A.S. Dadayan, M. Israyelyan, H.I. Hakobyan, Z. Mardiyan

Synthesis of -heterocyclic substituted (S)-alanine derivatives containing dipeptides and study of their antibacterial effect | International Scientific and Practical Conference “Biotechnology: Science and Practice, Innovation and Business” (“Armbiotech-SPIB-2021”).

T.H. Sargsyan, A.S. Sargsyan, S.M. Jamgaryan, E.A. Gyulumyan, L. Sahakyan, Yu.M. Danghyan, L. Stepanyan, Z. Mardiyan

Modeling of collagenase enzyme potential inhibitors (S)-β-morpholino-α-alanine containing dipeptide, target synthesis and in vitro study of their effect | International Scientific and Practical Conference “Biotechnology: Science and Practice, Innovation and Business” (“Armbiotech-SPIB-2021”)

T. Sargsyan, A. Sargsyan, Yu. Danghyan, S. Jamgaryan, E. Gyulumyan, N. Hovhannisyan, A. Tsaturyan, А. Hovhannisyan, A.S. Saghyan

Modeling, synthesis and study of impact of N-t-Boc-(S)-β-[4-allyl-3-(pyridin-3'-yl)-5-thioxo-1,2,4-triazol-1-y]-α-alanyl-(s)-alanyl-glycyl-(S)-β-[4-allyl-3-(pyridin-3'-yl)-5-thioxo-1,2,4-triazol-1-yl]-α-alanine tetrapeptide on collagenase activity | I International Scientific Conference, Current State of Pharmacy and Prospectsof its Development, 2018, Yerevan Armenia, November 01-03

T. H. Sargsyan, A. H. Tsaturyan, А. М. Hovhannisyan, A. S. Saghyan

Modeling of dipeptides containing potential biologically active (s)-α-propargylgycine, disclosure of possible biological properties and targeted synthesis | Dutch peptide symposium 2017. p. 71 |

T. H. Sargsyan, N. A. Hovhannisyan, Yu. M. Danghyan, S. M. Djamgaryan, E. A. Gyulumyan, A. H. Tsaturyan, A. M. Hovhannisyan, A. S. Saghyan

Synthesis and PASS prediction novel biologically active short peptides | 15th Naples workshop on bioactive peptides, peptides: recent developments and future directions, Naples, Italy, 2016, June 23-25, 73
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