Moldova–Armenia Interdisciplinary Research on the Toxicological Evaluation of Nanoparticles for Food Safety

A joint Armenian-Moldovan project addresses a key challenge in sustainable agriculture and food safety by studying the toxicological effects of synthetic and natural nanoparticles. Due to their increasing use in food packaging, preservation systems, and food additives, assessing their biosafety at the cellular and systemic levels is becoming increasingly important. The Moldovan team has extensive experience in the synthesis, functionalization, and biofunctionalization of nanoparticles for food applications. The Armenian team complements this expertise with histology, immunology, and toxicology, using animal models to study toxin-induced organ changes and having experience working with mycotoxins, oxidative stress, and hypoxia. 

The project will leverage these strengths through in vivo toxicological studies of pristine and
biofunctionalized nanoparticles, combining histological and immunohistochemical methods to identify acute and chronic effects. Expected results include the creation of robust toxicity datasets, contributions to food safety standards, bilateral capacity building, and the training of young researchers. 

This collaboration will advance nanotoxicology and serve as a model for interdisciplinary research in support of sustainable agriculture and public health.