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  1. Main
  2. Employees
  3. Mikayel Martik Ginovyan
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mikayel.ginovyan@ysu.am

Mikayel Martik Ginovyan

Research Institute of Biology
Basic and Pathological Biochemistry Laboratory
Senior Researcher

Personal information

Date of birth
1988
Education
Faculty
Faculty of biology
Date
2013 - 2016
Degree name
PhD student
Institution
Yerevan State University
Faculty
Faculty of biology
Date
2011 - 2013
Degree name
Masters
Institution
Yerevan State University
Faculty
Faculty of biology
Date
2005 - 2009
Degree name
Bachelor
Scientific Rank/degree
Institution
Yerevan State University
Date
2018
Degree name
Candidate
Scientific Supervisor
Professor Armen Trchounian
Research Topic
Biochemical characteristics of some herbs from Armenian flora
Language skills
English
Русский
Work experience
Institution
Laboratory of Basic and Pathological Biochemistry, Research Institute of Biology, Yerevan State University
Period of time
2025 till now
Rank/degree
Senior Researcher
Institution
Laboratory of Basic and Pathological Biochemistry, Research Institute of Biology, Yerevan State University
Period of time
2019 - 2024
Rank/degree
Researcher
Institution
Laboratory of Basic and Pathological Biochemistry, Research Institute of Biology, Yerevan State University
Period of time
2016 - 2019
Rank/degree
Junior Researcher
Participation in international conferences and seminars
09/07/2022 - 14/07/2022
The Biochemistry Global Summit (the 25th IUBMB, 46th FEBS and 15th PABMB Congresses), Lisbon, Portugal
Portugal
18/06/2023 - 21/06/2023
ISBT Congress 2023 (33rd Regional ISBT Congress), Gothenburg, Sweden
Sweden
08/07/2023 - 12/07/2023
The 47th FEBS Congress, Tours, France
France
20/03/2024 - 21/03/2024
COST EURESTOP GENERAL MEETING, Rome, Italy
Italy
23/06/2024 - 27/06/2024
ISBT 38th Congress, Barcelona, Spain
Spain
29/06/2024 - 03/07/2024
FEBS 48th Congress, Milan, Italy
Italy
04/07/2024
COST Action CA21145 EURESTOP WG meeting, Brussels, Belgium
Belgium
Membership
Institution
COST Action CA21145, European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP) - Management committee member
Period of time
2023 till now
Institution
International Society of Blood Transfusion (ISBT)
Period of time
2023 till now
Institution
COST Action CA16112 (NutRedOx) MC Observer from COST Near neighbour Countries
Period of time
2019 - 2021
Institution
The American Society for Microbiology (ASM)
Period of time
2015 till now
Institution
Federation of European Biochemical Societies (FEBS)
Period of time
2013 till now

Publications

- Կատեգորիա -
Article
Inhibition of the PI3K signaling pathway in cancer cells by Agrimonia eupatoria L. ethanolic extract: identification of tricoumaroyl spermidine as a potential PI3K inhibitor
Mikayel Ginovyan
Smbat Gevorgyan
Hayarpi Javrushyan
Barbara Kusznierewicz
Izabela Koss-Mikołajczyk
Naira Sahakyan
Agnieszka Bartoszek
Nikolay Avtandilyan
BMC Complementary Medicine and Therapies
2026
1-27
https://www.scopus.com/pages/publications/105029219890?origin=resultslist
Article
Evaluating the Efficacy of Polyphenol‐Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression
Hayarpi Javrushyan
Gayane Petrosyan
Marika Mróz
Barbara Kusznierewicz
Yem Alharithi
Mikayel Ginovyan
Alina Maloyan
Nikolay Avtandilyan
The FASEB Journal
2026
e71651 - e71651
https://doi.org/10.1096/fj.202501773rrr
Article
Adapting the Cohn 6th cold ethanol fractionation method for small plasma pools: An innovative platform for developing hyperimmunoglobulin products against antibiotic-resistant infections in resource-limited settings
Mikayel Ginovyan
Gayane Kirakosyan
Transfusion and Apheresis Science
2025
104093
Article
Characterization and antibacterial/cytotoxic activity of silver nanoparticles synthesized from Dicranum scoparium moss extracts growing in Armenia
Gayane Semerjyan
Inesa Semerjyan
Mikayel Ginovyan
Nikolay Avtandilyan
AIMS Biophysics
2025
29−42
Article
Ribes nigrum leaf extract downregulates pro-inflammatory gene expression and regulates redox balance in microglial cells
Alvard Minasyan
Vivien Pires
Catherine Gondcaille
Mikayel Ginovyan
Marika Mróz
Stéphane Savary
Mustapha Cherkaoui-Malki
Barbara Kusznierewicz
Agnieszka Bartoszek
Pierre Andreoletti
Naira Sahakyan
BMC Complementary Medicine and Therapies
2025
1-17
Article
Elucidating the impact of Hypericum alpestre extract and L-NAME on the PI3K/Akt signaling pathway in A549 lung adenocarcinoma and MDA-MB-231 triple-negative breast cancer cells
Hayarpi Javrushyan
Mikayel Ginovyan
Tigran Harutyunyan
Smbat Gevorgyan
Zaruhi Karabekian
Alina Maloyan
Nikolay Avtandilyan
PLOS ONE
2025
e0303736
Article
The potential of blackcurrant, fig, and grape leaf extracts in the development of new preparations for overcoming antibiotic resistance and enhancing the efficacy of chemotherapeutic agents
Mikayel Ginovyan
Silvard Tadevosyan
Anahit Shirvanyan
Anush Babayan
Barbara Kusznierewicz
Izabela Koss-Mikołajczyk
Marika Mróz
Agnieszka Bartoszek
Naira Sahakyan
BMC Complementary Medicine and Therapies
2025
1-54
Article
A novel approach for synthesizing silver nanoparticles with antibacterial and cytotoxic activities using the leaf extract of hydroponically grown Moringa oleifera
Anush Aghajanyan
Marina Timotina
Tatevik Manutsyan
Ani Harutyunyan
Mikayel Ginovyan
Robin Schubert
Sofiya Aydinyan
Karen Trchounian
Lilit Gabrielyan
Liana Gabrielyan
Scientific Reports
2025
1-18
Conference
Modulating antibiotic efficacy: the role of Teucrium polium in disrupting bacterial resistance mechanisms
Silvard Tadevosyan
Anush Babayan
Mikayel Ginovyan
Naira Sahakyan
2025
1308 - 1308
https://fems-microbiology.org/opportunities/fems-micro-milan-2025-congress-and-…
Conference
Emodin inhibits HIF-1α expression in MDA-MB- 231 cells via suppression of the PI3K/Akt/mTOR pathway
S. Hovhannisyan
M. Ginovyan
N. Avtandilyan
2025
314-315
https://2025.febscongress.org/about-febs-congresses
Conference
Hypericum alpestre Extract and L-NAME Suppress PI3K/Akt Pathway and Enhance Apoptosis in Lung and Breast Cancer Cells
Svetlana Hovhannisyan
Gayane Petrosyan
Hayarpi Javrushyan
Mikayel Ginovyan
Nikolay Avtandilyan
2025
146-146
https://journals.ysu.am/index.php/jisees/issue/view/SI_1_2025
Article
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L-arginine
Mikayel Ginovyan
Hayarpi Javrushyan
Hasmik Karapetyan
Izabela Koss‐Mikołajczyk
Barbara Kusznierewicz
Anna Grigoryan
Alina Maloyan
Agnieszka Bartoszek
Nikolay Avtandilyan
Cell Biochemistry and Function
2024
1-21
Article
5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches
Mikayel Ginovyan
Hayarpi Javrushyan
Svetlana Hovhannisyan
Edita Nadiryan
Gohar Sevoyan
Tigran Harutyunyan
Smbat Gevorgyan
Zaruhi Karabekian
Alina Maloyan
Nikolay Avtandilyan
Scientific Reports
2024
1-16
Article
Royal Jelly–Mediated Silver Nanoparticles Show Promising Anticancer Effect on HeLa and A549 Cells Through Modulation of the VEGFa/PI3K/Akt/MMP-2 Pathway
Meri Kocharyan
Syuzan Marutyan
Edita Nadiryan
Mikayel Ginovyan
Hayarpi Javrushyan
Seda Marutyan
Nikolay Avtandilyan
Applied Organometallic Chemistry
2024
1-11
Conference
The combination of herbs and chemotherapeutic agents inhibits tumor progression via down-regulation of the TNFa-VEGFa/PI3K/Akt/NOS/COX-2-MMP-2 pathway in DMBA-induced breast cancer in rats
N. Avtandilyan
M. Kocharyan
S. Hovhannisyan
S. Gevorgyan
H. Javrushyan
M. Ginovyan
A. Maloyan
2024
276-276
https://2024.eacr.org/
Conference
From metabolomics to medicine: exploiting the functional potential of plant extracts in human health, with emphasis on Ribes nigrum, Ficus carica and Vitis vinifera
S. Tadevosyan
M. Ginovyan
N. Avtandilyan
A. Shirvanyan
A. Bartoszek
N. Sahakyan
2024
164-165
https://2024.febscongress.org/
Conference
From agro-bio-waste to application: the power of bilberry aerial part extract as anti-cancer and antibiotic-modulating agent
N. Sahakyan
M. Ginovyan
A. Babayan
A. Shirvanyan
A. Minasyan
B. Kusznierewicz
I. Koss-Mikołajczyk
N. Avtandilyan
A. Bartoszek
2024
179-180
https://2024.febscongress.org/
Conference
Harnessing plant extracts to overcome antibiotic resistance: leaf extracts of Ribes nigrum, Ficus carica, and Vitis vinifera as resistance modifiers of E. coli strains
M. Ginovyan
A. Shirvanyan
S. Tadevosyan
A. Babayan
B. Kusznierewicz
N. Avtandilyan
A. Bartoszek
N. Sahakyan
2024
338 - 338
https://2024.febscongress.org/
Conference
The cytotoxicity and antibacterial activity of Moringa oleifera-mediated silver nanoparticles
M. Timotina
T. Manutsyan
M. Ginovyan
K. Trchounian
L. Gabrielyan
A. Aghajanyan
2024
442-442
https://2024.febscongress.org/
Conference
Investigating the anticancer advantages of pairing Rumex obtusifolius herb extract with 5-fluorouracil against breast cancer in vivo
S. Hovhannisyan
M. Ginovyan
N. Avtandilyan
2024
321-322
https://2024.febscongress.org/

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