General information
The vaginal microbiome plays a vital role in maintaining mucosal health, immunity, and pH stability in the female reproductive tract. Disruption of this delicate microbial balance, often marked by a decline in lactic acid–producing bacteria, has been associated with vaginosis, vaginitis, and related reproductive complications. This study utilizes an integrative approach, employing both MALDI-TOF MS and whole genome sequencing to isolate, identify, and evaluate the probiotic potential of key vaginal microbes. Specific attention is given to lactic acid bacteria, known for their ability to inhibit pathogens and restore microbial homeostasis. The goal of this research is to identify all isolated microorganisms and reveal genes responsible for probiotic properties. These microbes could serve as safe and effective alternatives to antibiotic treatments for common vaginal disorders.
