General information
The goal of the proposed project is to synthesize homo- and heterometallic complexes with bioessential metals in order to discover new bioactive coordination compounds. Bioessential metal’s carboxylates receive particular attention because they are adaptable building blocks that can create complexes with a variety of stable structures. Biologically active ligands containing donor atoms of oxygen, nitrogen, and/or sulfur-which are known to be crucial in regulating biological activity will be used synthesis of these compounds. The study will concentrate on creating novel synthetic methods for combining these ligands with bioessential metals in an effort to strengthen their possible antibacterial and antitumor effects. The project intends to advance metal-based therapeutics and offer insights into the structure–activity relationships that govern their bioactivity by utilizing the special coordination chemistry and functional characteristics of bioessential metals, such as luminescence, redox activity, and high coordination numbers.
