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  1. Main
  2. Employees
  3. Ashot S Saghyan
download PDF
34-10
saghyan@ysu.am
Ashot
S
Saghyan
Institute of Pharmacy
Chair of Pharmaceutical Chemistry and Pharmacognosy
Professor

Personal information

Date of birth
1957
Education
Institution
Yerevan State University
Faculty
Faculty of Chemistry
Date
1973 - 1978
Degree name
Qualified specialist
Scientific Rank/degree
Institution
Yerevan State University
Date
2003
Degree name
Professor
Specialty
Chemical sciences
Institution
Yerevan State University
Date
1997
Degree name
Doctor
Specialty
Chemical sciences
Research Topic
Asymmetric synthesis of non-proteinogenic (S)- and (R)- alpha amino acids via chiral dehydroamino acids complex of Co3+ and Ni 2+
Institution
A.N.Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences
Date
1985
Degree name
Postgraduate
Scientific Supervisor
Yu. N Belokon
Research Topic
Synthesis and reactivity of complexes of Schiff bases of dehydroamino acids with Co(III) and Ni(II) ions
Language skills
Русский
English

Publications

- Կատեգորիա -
Article
Binding of G-quadruplex DNA and serum albumins by synthetic non-proteinogenic amino acids: Implications for c-Myc-related anticancer activity and drug delivery
Hayarpi Simonyan
Satenik Petrosyan
Lusine Sahakyan
Gagik Melikyan
Ashot Sagyan
Rosanna Palumbo
Caterina Vicidomini
Pasqualina Liana Scognamiglio
Giovanni N. Roviello
Molecular Therapy Nucleic Acids
2025
102478
Article
Unnatural Phosphorus-Containing α-Amino Acids and Their N-FMOC Derivatives: Synthesis and In Vitro Investigation of Anticholinesterase Activity
Ani S. Dadayan
Anna F. Mkrtchyan
Atravazd S. Poghosyan
Slavik A. Dadayan
Lala A. Stepanyan
Monika H. Israyelyan
Anna S. Tovmasyan
Avetis H. Tsaturyan
Nona A. Hovhannisyan
Vigen O. Topuzyan
Tatevik H. Sargsyan
Ashot S. Saghyan
ChemistrySelect
2024
1-10
Article
BSA Binding and Aggregate Formation of a Synthetic Amino Acid with Potential for Promoting Fibroblast Proliferation: An In Silico, CD Spectroscopic, DLS, and Cellular Study
Hayarpi Simonyan
Rosanna Palumbo
Satenik Petrosyan
Anna Mkrtchyan
Armen Galstyan
Ashot Saghyan
Pasqualina Liana Scognamiglio
Caterina Vicidomini
Marta Fik-Jaskólka
Giovanni N. Roviello
Biomolecules
2024
579
Article
The Synthesis and in vitro Study of 9-fluorenylmethoxycarbonyl Protected Non-Protein Amino Acids Antimicrobial Activity
T.H. Sargsyan
L.A. Stepanyan
M.H. Israyelyan
H.I. Hakobyan
S.M. Jamgaryan
A.A. Gasparyan
A.S. Saghyan
Eurasian Chemico-Technological Journal
2024
235-240
Article
Synthesis and evaluation of new mono- and binuclear salen complexes for the Cα-alkylation reaction of amino acid substrates as chiral phase transfer catalysts
Anahit M. Hovhannisyan
Anna S. Tovmasyan
Anna F. Mkrtchyan
Karapet R. Ghazaryan
Ela V. Minasyan
Olgert L. Dallakyan
Mikayel S. Chobanyan
Hayk Zakaryan
Giovanni N. Roviello
Ashot S. Saghyan
Molecular Catalysis
2024
114618
Article
Ion-chromatographic determination of common anions in drinking water in some regions of the Republic of Armenia
Avetis Tsaturyan
Lusine Sahakyan
Lusine Hayrapetyan
Ela Minasyan
Ani Chakhoyan
Sergey Hayrapetyan
Ashot Saghyan
Pharmacia
2024
e135658
Article
Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups
Artavazd S. Poghosyan
Ashot S Saghyan
Peter Langer
Ela V. Minasyan
Karapet R. Ghazaryan
Anahit M. Hovhannisyan
Anna F Mkrtchyan
Volodya Mirzoyan
Emma A. Khachatryan
Amino Acids
2024
67
Article
Synthesis, Characterization, and Study of Catalytic Activity of Chiral Cu(II) and Ni(II) Salen Complexes in the α-Amino Acid C-α Alkylation Reaction
Anna S. Tovmasyan
Anna F. Mkrtchyan
Hamlet N. Khachatryan
Mary V. Hayrapetyan
Robert M. Hakobyan
Artavazd S. Poghosyan
Avetis H. Tsaturyan
Ela V. Minasyan
Viktor I. Maleev
Vladimir A. Larionov
Armen G. Ayvazyan
Norio Shibata
Giovanni N. Roviello
Ashot S. Saghyan
Molecules
2023
1180
Article
Development of the technology for producing water-soluble melanin from waste of vinary production and the study of its physicochemical properties
Armen E. Aghajanyan
Artur A. Hambardzumyan
Ela V. Minasyan
Avetis H. Tsaturyan
Ani M. Paloyan
Sona V. Avetisyan
Anichka S. Hovsepyan
Ashot S. Saghyan
European Food Research and Technology
2022
485-495
Article
Sequential Heck Cross-Coupling and Hydrothiolation Reactions Taking Place in the Ligand Sphere of a Chiral Dehydroalanine Ni(II) Complex: Asymmetric Route to β‑Aryl Substituted Cysteines
Zalina T. Gugkaeva
Zorayr Z. Mardiyan
Alexander F. Smol’yakov
Artavazd S. Poghosyan,
Ashot S. Saghyan
Victor I. Maleev
Vladimir A. Larionov
Organic Letters
2022
6230−6235
Article
SYNTHESIS OF (S)-ALANYL-(S)-β-(THIAZOL-2-YL-CARBAMOYL)-α-ALANINE, DIPEPTIDE CONTAINING IT AND IN VITRO INVESTIGATION OF THE ANTIFUNGAL ACTIVITY
TATEVIK SARGSYAN
HEGHINE HAKOBYAN
ZORAYR MARDIYAN
NUNE KHACHATURYAN
SONA GEVORGYAN
SILVA JAMGARYAN
ENZHENA GYULUMYAN
YURI DANGHYAN
ASHOT SAGHYAN
Farmacia
2022
1148-1154
Article
Synthesis of enantiomerically enriched non-protein α-amino acids and their study as aldose reductase inhibitors
Anna F. Mkrtchyan
Liana A. Hayriyan
Armen S. Sargsyan
Ani M. Paloyan
Anna S. Tovmasyan
Ani J. Karapetyan
Artur A. Hambardzumyan
Nelli A. Hovhannisyan
Henrik A. Panosyan
Hamlet N. Khachatryan
Ani S. Dadayan
Ashot S. Saghyan
Synthetic Communications
2021
1433–1450
Article
Synthesis of Biomimetic Polymers Based on Nonproteinogenic α-Amino Acids
Nino Zavradashvili
Giuli Otinashvili
David Tugushi
Tengiz Kantaria
Temur Kantaria
Nino Kupatadze
Ekaterina Chkhaidze
Nino Neparidze
Ashot Saghyan
Anna Mkrtchyan
Artavazd Poghosyan
BULLETIN OF THE GEORGIAN NATIONAL ACADEMY OF SCIENCES
2021
41-47
Article
New Cationic Polymers Composed of Non-Proteinogenic α-Amino Acids
NINO ZAVRADASHVILI
GIULI OTINASHVILI
TEMUR KANTARIA
NINO KUPATADZE
DAVID TUGUSHI
ASHOT SAGHYAN
ANNA MKRTCHYAN
SERGEY POGHOSYAN
RAMAZ KATSARAVA
Advanced Materials, Polymers, and Composites: New Research on Properties, Techniques, and Applications
2021
277-287
Article
Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity
Marta A.Fik-Jaskółka
Anna F.Mkrtchyan
Ashot S.Saghyan
Rosanna Palumbo
Agnieszka Belter
Liana A.Hayriyan
Hayarpi Simonyan
ValentinaRoviello
Giovanni N.Roviello
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
2020
117884
Article
The charge-assisted hydrogen-bonded organic framework (CAHOF) self-assembled from the conjugated acid of tetrakis(4-aminophenyl)methane and 2,6-naphthalenedisulfonate as a new class of recyclable Brønsted acid catalysts
Saghyan A.S.
Svetlana A. Kuznetsova
Alexander S. Gak
Yulia V. Nelyubina
Vladimir Larionov
Han Li
Michael North
Vladimir P. Zhereb
Alexander F. Smol'yakov
Artem O. Dmitrienko
Michael G. Medvedev
Igor S. Gerasimov
Yuri N. Beլokon
Beilstein Journal of Organic Chemistry
2020
1124–1134
Article
Asymmetric synthesis, biological activity and molecular docking studies of some unsaturated α-amino acids, derivatives of glycine, allylglycine and propargylglycine
A. F. Mkrtchyan
A. S. Saghyan
L. A. Hayriyan
A. S. Sargsyan
A. J. Karapetyan
A. S. Tovmasyan
A. H. Tsaturyan
E. V. Minasyan
A. S. Poghosyan
A. M. Paloyan
H. A. Panosyan
Lu. Yu. Sahakyan
Journal of Molecular Structure
2020
127850
Article
Biological macromolecule binding and anticancer activity of synthetic alkyne-containing L-phenylalanine derivatives
Marta A. Fik-Jaskółka
Anna F. Mkrtchyan
Ashot S. Saghyan
Rosanna Palumbo
Agnieszka Belter
Liana A. Hayriyan
Hayarpi Simonyan
Valentina Roviello
Giovanni N. Roviello
Amino Acids
2020
755–769
Article
Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
Yupiao Zou
Jianlin Han
Ashot S. Saghyan
Anna F. Mkrtchyan
Hiroyuki Konno
Hiroki Moriwaki
Kunisuke Izawa
Vadim A. Soloshonok
Molecules
2020
2739
Article
Using the Ni-[(Benzylprolyl)amino]benzophenone complex in the Glaser reaction for the synthesis of bis α-amino acids
Anna F. Mkrtchyan
Liana A. Hayriyan
Ani J. Karapetyan
Anna S. Tovmasyan
Avetis H. Tsaturyan
Victor N. Khrustalev
Viktor I. Maleev
Ashot S. Saghyan
New Journal of Chemistry
2020
8

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