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  1. Main
  2. Employees
  3. Lusine Yurik Sahakyan
download PDF
38-50
(060) 71-04-10
lusine_sahakyan@ysu.am
Lusine
Yurik
Sahakyan
Scientific and Educational Center for Control and Monitoring of the Quality of Medicines
Expert

Personal information

Date of birth
1978
Scientific interests
  • Development of optimal methods for asymmetric synthesis of non-protein α-amino acids, study of bioactivity
  • Development and validation of qualitative and quantitative instrumental analysis methods for bioactive compounds (HPLC, GC, MS, IR)
Education
Institution
Yerevan State University
Faculty
Institute of Pharmacy
Date
2017 - 2018
Degree name
Applicant
Institution
S. Avdalbekyan National Institute of Health
Faculty
postgraduate qualification
Date
2004 - 2005
Degree name
Qualified specialist
Institution
Yerevan State University
Faculty
Chemical faculty
Date
1996 - 2001
Degree name
Qualified specialist
Scientific Rank/degree
Institution
Yerevan State University
Date
2021
Degree name
Candidate
Specialty
Pharmaceutical sciences
Scientific Supervisor
President of the National Academy of Sciences of the Republic of Armenia, Professor Ashot S. Saghyan
Research Topic
BIOMIMETIC SYNTHESIS OF HETEROCYCLIC NON-PROTEIN ANALOGUES OF α-AMINOBUTYRIC ACID, STUDY OF ANTIOXIDANT AND MEMBRANE PROTECTIVE PROPERTIES
Language skills
Հայերեն
English
Русский
Work experience
Institution
YSU, Institute of Pharmacy, Scientific-educational center for drug quality control and monitoring
Period of time
2021 till now
Rank/degree
Expert
Institution
YSU, Institute of Pharmacy, Chair of Biomedicine
Period of time
2017 till now
Rank/degree
Assistant Professor
Institution
Scientific and Production Center “Armbiotechnology” of NAS, RA
Period of time
2016 - 2019
Rank/degree
Rresearcher
Institution
"Arpimed" LLC
Period of time
2014 - 2014
Rank/degree
Specialist of Quality Assurance Department
Institution
YSU, Chair of "Pharmaceutical Chemistry"
Period of time
2014 - 2017
Rank/degree
Laboratory assistant
Institution
"Arpimed" LLC
Period of time
2010 - 2014
Rank/degree
Head of Liquid Pharmaceuticals Department
Institution
YSU, "Synthesis of Heterocyclic Amino Acids" Research Laboratory
Period of time
2009 - 2019
Rank/degree
Senior Laboratory Assistant
Institution
YSU, Basic Laboratory of "Synthesis of Heterocyclic Compounds Containing Nitrogen, Oxygen, Sulfur"
Period of time
2005 - 2009
Rank/degree
Senior Laboratory Assistant
Institution
"Modern Cosmetic Laboratory" LLC, Abovyan
Period of time
2003 - 2008
Rank/degree
Consultant specialist
Institution
"Arpimed" LLC, Quality Control Laboratory
Period of time
2001 - 2004
Rank/degree
Chemist-analyst
Participation in international conferences and seminars
06/07/2024 - 16/07/2024
scientific travel
University of Naples Federico II, National Research Council (CNR)
Italy
28/07/2022 - 08/08/2022
scientific travel
University of Naples Federico II, National Research Council (CNR)
Italy
Membership
Institution
Scientific Council of the Institute of Pharmacy
Period of time
2021 till now
Institution
Member of the Ethics Committee for Clinical Drug Research, Ministry of Health, RA
Period of time
2018 - 2024

Publications

- Կատեգորիա -
Article
Improvement of biomass and biohydrogen generation in Parachlorella kessleri using ethanol and brewery production wastes as cultivation media
Jemma Manoyan
Diana Hakobyan
Lilit Gabrielyan
Iren Shahazizyan
Lusine Sahakyan
Ela Minasyan
Liana Gabrielyan
International Journal of Hydrogen Energy
2025
400-410
Article
Binding of G-quadruplex DNA and serum albumins by synthetic non-proteinogenic amino acids: Implications for c-Myc-related anticancer activity and drug delivery
Hayarpi Simonyan
Satenik Petrosyan
Lusine Sahakyan
Gagik Melikyan
Ashot Sagyan
Rosanna Palumbo
Caterina Vicidomini
Pasqualina Liana Scognamiglio
Giovanni N. Roviello
Molecular Therapy Nucleic Acids
2025
102478
Article
COMPARATIVE ANALYSIS OF METHODS FOR THE DETECTION AND QUANTITATIVE DETERMINATION OF ETHYL ALCOHOL IN THE BODY
Satenik Gh. Petrosyan
Lusine Yu. Sahakyan
Nelly A. Kirakosyan
Proceedings of the YSU B: Chemical and Biological Sciences
2024
1-8
Article
Ion-chromatographic determination of common anions in drinking water in some regions of the Republic of Armenia
Avetis Tsaturyan
Lusine Sahakyan
Lusine Hayrapetyan
Ela Minasyan
Ani Chakhoyan
Sergey Hayrapetyan
Ashot Saghyan
Pharmacia
2024
e135658
Article
Detection and development of a quantitation method for undeclared compounds in antidiabetic biologically active additives and its validation by high performance liquid chromatography
Virab Gurgen Kirakosyan
Avetis Hovhannes Tsaturyan
Lilit Eduard Poghosyan
Ella Vardan Minasyan
Hayk Razmik Petrosyan
Lusine Yurik Sahakyan
Tatevik Hovhannes Sargsyan
Pharmacia
2022
45-50
Article
Asymmetric Synthesis of Derivatives of Alanine via Michael Addition Reaction and their Biological Study
Mkrtchyan Anna
Tovmasyan Anna
Paloyan Ani
Sargsyan Armen
Simonyan Hayarpi
Sahakyan Lusine
Petrosyan Satenik
Hayriyan Liana
Sargsyan Tatevik
Synlett
2022
2013-2018
Article
ISOLATION, IDENTIFICATION AND QUANTITATIVE DETERMINATION OF NIFEDIPINE FROM BIOLOGICAL MATERIAL
S.Gh. Petrosyan
L.Yu. Sahakyan
V.G. Kirakosyan
E.V. Minasyan
S. E. Sardaryan
Proceedings of the YSU B: Chemical and Biological Sciences
2021
204-211
Article
Asymmetric synthesis, biological activity and molecular docking studies of some unsaturated α-amino acids, derivatives of glycine, allylglycine and propargylglycine
A. F. Mkrtchyan
A. S. Saghyan
L. A. Hayriyan
A. S. Sargsyan
A. J. Karapetyan
A. S. Tovmasyan
A. H. Tsaturyan
E. V. Minasyan
A. S. Poghosyan
A. M. Paloyan
H. A. Panosyan
Lu. Yu. Sahakyan
Journal of Molecular Structure
2020
127850
Article
Исследование асимметрического нуклеофильного бис-присоеденения дегидроаланиновых комплексов Ni(II)
Петросян С. Г.
Симонян А. М
Мкртчян А. Ф.
Саакян Л. Ю.
Цатурян A. O.
Сагян А. С.
Հայաստանի քիմիական հանդես
2020
213-222
Article
СРАВНИТЕЛЬНОЕ ИЗУЧЕНИЕ АНТИОКСИДАНТНОЙ АКТИВНОСТИ β-ГЕТЕРОЦИКЛИЧЕСКИ ЗАМЕЩЕННЫХ АНАЛОГОВ α-АМИНОМАСЛЯНОЙ КИСЛОТЫ И НЕКОТОРЫХ ЭНДОГЕННЫХ АНТИОКСИДАНТОВ
Саакян Л.Ю.
Симонян Г.М.
Симонян Р.М.
Симонян М.А.
Секоян Э.С.
Сагян А.С.
Տեսական և կլինիկական բժշկության հարցեր
2018
3-6
http://pananarm.info/
Article
Асимметрический синтез (2S,3S)-3-(2-тиоксо-2,3-дигидробензимидазол-1-ил)-2-аминомасляной кислоты
Л.Ю. Саакян
Химический Журнал Армении
2018
117-125
Article
Сравнительное ингибирующее действие β-гетероциклически замещенного аналога α-аминомасляной кислоты и мексидола на процесс рилизинга изоформ NADPH-оксидаз нейрональных мембран
Л.Ю. Саакян
Медицинская наука Армении
2018
50-58
Article
Механизмы мембранопротекторного действия нового β-гетероциклически замещенного синтетического аналогоа α-аминомасляной кислоты при оксидативно-нитрозативном стрессе
Л.Ю. Саакян
Р.М. Симонян
Г.М. Симонян
М.А. Симонян
Э.С. Секоян
А.С. Сагян
Տեսական և կլինիկական բժշկության հարցեր
2018
26-31
Article
АНТИОКСИДАНТНАЯ АКТИВНОСТЬ И МЕХАНИЗМЫ МЕМБРАНОСТАБИЛИЗИРУЮЩЕГО ДЕЙСТВИЯ НОВОГО β-ГЕТЕРОЦИКЛИЧЕСКИ ЗАМЕЩЕННОГО АНАЛОГА α-АМИНОМАСЛЯНОЙ КИСЛОТЫ
Л. Ю. Саакян
Г. М. Симонян
Р. М. Симонян
Э. С. Секоян
А. С. Сагян
Տեսական և կլինիկական բժշկության հարցեր
2017
64-67
http://www.pananarm.info/
Article
Асимметрический синтез новых гетероциклически замещенных аналогов α-аминомасляной кислоты, содержащих замещенные триазольные группы в боковом радикале
А.С.Сагиян
Л.Ю.Саакян
А.М.Симонян
С.Г.Петросян
А.Ф.Мкртчян
М.А.Самвелян
Т.В.Кочикян
П,Лангер
Химический Журнал Армении
2017
71-81
http://www.flib.sci.am/eng/Qimia/Frame.html
Article
Асимметрический синтез новых гетероциклически замещенных аналогов (S)-α-аланина, содержащих 3,4-дизамещенные -5-тиоксо-1,2,4-триазолы в боковом радикале
А.М.Симонян
А.С.Сагиян
Л.Ю.Саакян
Н.Н.Багян
А.О.Восканян
Ж.Н.Сарибекян
М.А.Самвелян
Т.В.Кочикян
Химический Журнал Армении
2017
82-91
http://www.flib.sci.am/eng/Qimia/Frame.html
Article
Механизмы протекторного действия β-гетероциклически замещенного аналогоа α-аминомасляной кислоты на клеточные и субклеточные мембраны
Л.Ю.Саакян
Р.М.Симонян
Г.М.Симонян
М.А.Симонян
Э.С.Секоян
А.С.Сагян
Տեսական և կլինիկական բժշկության հարցեր
2017
16-19
http://www.pananarm.info/
Article
ПРОТЕКТОРНЫЙ ЭФФЕКТ ДИМЕТИЛСУЛЬФОКСИДА НА ИЗОФОРМЫ NADPH-ОКСИДАЗЫ БИОМЕМБРАН
Р. М. Симонян
Л. Ю. Саакян
Г. М. Симонян
М. А. Симонян
Э. С. Секоян
А. С. Сагиян
Տեսական և կլինիկական բժշկության հարցեր
2016
61-64
http://www.pananarm.info/
Conference
Asymmetric synthesis of potential biologically active new heterocyclic analogs of (s)--alanine containing 3,4-substituted 5-thioxo-1,2,4- triazoles in the side-chain radical
H.M. Simonyan
L.Yu. Sahakyan
S.Gh․ Petrosyan
A.F. Mkrtchyan
N.N. Baghyan,
J.N. Saribekyan
A.S. Saghyan
Conference
Asymmetric synthesis of new heterocyclic analogs of alpha-aminopropionic acid and alpha-aminobutyric acid via Michael nucleophilic addition reactions
Hayarpi Simonyan
Lusine Sahakyan
Anna Mkrtchyan
Satenik Petrosyan
Ashot Saghyan

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